Endocrinology Is Fascinating

نویسنده

  • Fereidoun Azizi
چکیده

Endocrinology defined earlier as the study of cell communication via messenger molecules or hormones transversing extracellular space, now extends to inter and intra cellular spaces. Development of the understanding of functioning of endocrine glands parallels the evolution of clinical sciences in the history of medicine. For example Rhazes, died 925 A.D, discussed in detail the sex organs and contraception (1); Avicenna, died in 1037, gave a good account of diabetes, described 22 conditions for polyuria in addition to diabetes, and for the first time, pointed out diabetes insipidus (2, 3). Avicenna and Jurjani documented and introduced the association between exophthalmos and goiter 8 centuries before Pary, Graves and Basedow (4). Around 100 years ago, Starling proposed the term hormone to describe secretion of a substance by the small intestine into the bloodstream. Others showed that replacement of thyroid extract and insulin could treat hypothyroidism and diabetes mellitus successfully. Nowadays, advances in cell biology, molecular biology, immunology and genetics explain the mechanism of hormone secretion, action and the pathophysiology of endocrine diseases.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Pancreatic neuroendocrine tumors: the basics, the gray zone, and the target

Pancreatic neuroendocrine tumors (PanNETs) manifest with a range of symptoms and pose a therapeutic challenge. A team approach, in which many specialists come together, is necessary in the quest for the best patient-tailored treatment. Disciplines such as oncology, surgery, basic science, endocrinology, radiology, and nuclear medicine need to work side by side, equally contributing to patient c...

متن کامل

Sarcopenia in Endocrine Disorders – The Iceberg or Its Tip?

Endocrine myopathies represent disorders of the musculoskeletal system that significantly impair the state of health. Sarcopenia is their pathophysiological common denominator. Recent reports have shown that endocrine disorders, even when subclinical, may also be associated with tendinopathies. It may thus be suggested that both hormones and hormonal disorders have complex actions on the muscul...

متن کامل

Recent advances in the molecular genetics of congenital and acquired primary adrenocortical failure.

In recent years there have been many advances in our understanding of the molecular pathogenesis of both congenital and acquired adrenocortical failure (autoimmune or otherwise). As well as providing some fascinating insights into adrenal gland development and steroid hormone biosynthesis, the recognition of these various distinct disorders, either at a clinical or molecular genetic level, ofte...

متن کامل

Dr. Kenneth R. Feingold joins our Board of Associate Editors!

We are very happy and proud to announce that Dr. Kenneth R. Feingold has joined our Board of Associate Editors. Due to his outstanding expertise in skin physiology, we are convinced that his contribution will have a major impact for the future development of our journal. At present, Dr. Feingold is Professor of Medicine and Dermatology at the Department of Medicine of the University of Californ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2016